Inbound and Outbound Open Innovation: Organization and Performances


  • Francesca Michelino Università degli Studi di Salerno
  • Mauro Caputo Università degli Studi di Salerno
  • Antonello Cammarano Università degli Studi di Salerno
  • Emilia Lamberti Università degli Studi di Roma Tor Vergata



Open innovation, Inbound open innovation, Outbound open innovation, R&D organization, Financial performances, Bio-pharmaceutical industry.


The aim of the paper is to analyse the relationships between the openness degree of companies and their 1) context features, 2) R&D organization and 3) financial performances. The openness degree is defined after a pecuniary approach, involving all the transactions in the innovation market. Hypotheses are formulated and, then, tested on a sample of 126 world top R&D spending bio-pharmaceutical companies for the period 2008-2012. Open innovation is more pervasive among small and young companies, for most of which it represents the very core business. Inbound and outbound practices have a similar diffusion in terms of number of companies adopting them, but the cumulative values of inbound flows are higher, whereas outbound flows are more relevant when compared to the total business of the firms. Inbound practices are substitutive to internal R&D activities, while outbound ones are complementary to internal development. The performances of companies have an inverted-U shape trend versus inbound practices and a fundamentally decreasing trend versus outbound ones.


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Author Biographies

Francesca Michelino, Università degli Studi di Salerno

Department of Industrial Engineering

Adjunct Professor of Marketing and Supply Chain Management

Mauro Caputo, Università degli Studi di Salerno

Department of Industrial Engineering

Full Professor of Innovation and Technology Management

Antonello Cammarano, Università degli Studi di Salerno

PhD Student in Innovation Economy and Engineering

Emilia Lamberti, Università degli Studi di Roma Tor Vergata

PhD Student in Enterprise Engineering


AHN, J. M., Mortara, L., Minshall, T. (2013). The Effects of Open Innovation on Firm Performance: A Capacity Approach. STI Policy Review, 4(1), 74-93. Available at SSRN:

BARGE-GIL, A. (2010). Open, semi-open and closed innovators: towards an explanation of degree of openness. Industry and Innovation, 17(6), 577-607. doi:

BIANCHI, M., Cavaliere, A., Chiaroni, D., Frattini, F., Chiesa, V. (2011). Organisational modes for open innovation in the bio-pharmaceutical industry: an exploratory analysis. Technovation, 31(1), 22-33. doi: 10.1016/j.technovation.2010.03.002

CHESBROUGH, H. (2003). Open Innovation: The New Imperative for Creating and Profiting from Technology. Harvard Business School Press, Boston.

CHESBROUGH, H., Crowther, A. K. (2006). Beyond high-tech: early adopters of open innovation in other industries. R&D Management, 36(3), 229-236. doi:

CHIARONI, D., Chiesa, V., Frattini, F. (2008). Patterns of collaboration along the bio-pharmaceutical innovation process. Journal of Business Chemistry, 5(1), 7-22. Available at

CHIARONI, D., Chiesa, V., Frattini, F. (2009). Investigating the adoption of open innovation in the biopharmaceutical industry: a framework and an empirical analysis. European Journal of Innovation Management, 12(3), 285-305. doi:

COHEN, W. M., Levinthal, D. A. (1990). Absorptive capacity: A new perspective on learning and innovation. Administrative Science Quarterly, 35(1), 128-152. doi:

COOKE, P. (2005). Regionally asymmetric knowledge capabilities and open innovation exploring “Globalisation 2” - a new model of industry organization. Research Policy, 34(8), 1128-1149. doi:

DAHLANDER, L., Gann, D. M. (2007). How open is innovation?. Paper Presented at the DRUID Summer Conference. 18 June 2007. Copenhagen, Denmark.

DAHLANDER, L., Gann, D. M. (2010). How open is innovation?. Research Policy, 39(6), 699-709. doi:

DODGSON, M., Gann, D. M., Salter, A. (2006). The role of technology in the shift towards open innovation: the case of Procter & Gamble. R&D Management, 36(3), 333-346. doi:

ENKEL, E., Lenz, A. (2009). Open innovation metrics system. Paper Presented at the R&D Management Conference. 21-24 June 2009. Vienna, Austria.

FAEMS, D., de Visser, M., Andries, P., van Looy, B. (2010). Technology alliance portfolios and financial performance: value-enhancing and cost-increasing effects of open innovation. Journal of Product Innovation Management, 27(6), 785-796. doi:

FETTERHOFF, T. J., Voelkel, D. (2006). Managing open innovation in biotechnology. Research-Technology Management, 49(3), 14-18. Available at

GASSMANN, O. (2006). Opening up the innovation process: towards an agenda. R&D Management, 36(3), 223-228. doi:

GASSMANN, O., Enkel, E. (2004). Towards a theory of open innovation: three core process archetypes. Paper Presented at the R&D Management Conference. 6-9 July 2004. Lisbon, Portugal.

GASSMANN, O., Reepmeyer, G., von Zedtwitz, M. (2008). Leading Pharmaceutical Innovation: Trends and Drivers for Growth in the Pharmaceutical Industry. Springer, Berlin.

HUIZINGH, E. K. R. E. (2011). Open innovation: state of the art and future perspectives. Technovation, 31(1), 2-9. doi:

HUNG, K.-P., Chiang, Y.-H. (2010). Open innovation proclivity, entrepreneurial orientation, and perceived firm performance. International Journal of Technology Management, 52(3-4), 257-274. doi: 10.1504/IJTM.2010.035976

HWANG, J., Lee, Y. (2010). External knowledge search, innovative performance and productivity in the Korean ICT sector. Telecommunications Policy, 34(10), 562-571. doi:

IDRISSIA, M. O., Amaraa, N., Landrya, R. (2012). SMEs’ Degree of Openness: The Case of Manufacturing Industries. Journal of Technology Management & Innovation, 7(1), 186-210. doi:

ILI, S., Albers, A., Miller, S. (2010). Open innovation in the automotive industry. R&D Management, 40(3), 246-255. doi:

INAUEN, M., Schenker-Wicki, A. (2011). The impact of outside-in open innovation on innovation performance. European Journal of Innovation Management, 14(4), 496-520. doi:

JU, P.-H., Chen, D.-N., Yu, Y.-C., Wei, H.-L. (2013). Relationships among Open Innovation Processes, Entrepreneurial Orientation, and Organizational Performance of SMEs: The Moderating Role of Technological Turbulence. In: Kobylinski, A., Sobczak, A. (Eds.), Perspectives in Business Informatics Research - 12th International Conference, BIR 2013, Warsaw, Poland, September 23-25. Proceedings, Springer, pp. 140-160.

KATZ, R., Allen, T. J. (1982). Investigating the Not Invented Here (NIH) syndrome: A look at the performance, tenure, and communication patterns of 50 R&D Project Groups. R&D Management, 12(1), 7-20. doi: 10.1111/j.1467-9310.1982.tb00478.x

KEUPP, M. M., Gassmann, O. (2009). Determinants and archetype users of open innovation. R&D Management, 39(4), 331-341. doi:

KLEYN, D., Kitney, R., Atun, R. (2007). Partnership and innovation in the life sciences. International Journal of Innovation Management, 11(2), 323-347. doi:

KUMAR, N., Saqib, M. (1996). Firm size, opportunities for adaptation and in-house R&D activity in developing countries: the case of Indian manufacturing. Research Policy, 25(5), 713-722. doi:

LAURSEN, K., Salter, A. (2006). Open for innovation: the role of openness in explaining innovation performance among U.K. manufacturing firms. Strategic Management Journal, 27(2), 131-150. doi: 10.1002/smj.507

LAZZAROTTI, V., Manzini, R., Pellegrini, L. (2010). Open innovation models adopted in practice: an extensive study in Italy. Measuring Business Excellence, 14(4), 11-23. doi:

LEE, S., Park, G., Yoon, B., Park, J. (2010). Open innovation in SMEs - An intermediated network model. Research Policy, 39(2), 290-300. doi:

MICHELINO, F., Lamberti, E., Cammarano, A., Caputo, M. (2014a). Measuring open innovation in the bio-pharmaceutical industry. Creativity and Innovation Management (Article in Press). doi: 10.1111/caim.12072

MICHELINO, F., Cammarano, A., Lamberti, E., Caputo, M. (2014b). Open models for innovation of leading companies in high competitive industries. Proceedings of the 23rd International Business Information Management Association Conference - IBIMA. 13-14 May 2014. Valencia, Spain.

PODMETINA, D., Väätänen, J., Torkkeli, M. T., Smirnova, M. M. (2011). Open innovation in Russian firms: an empirical investigation of technology commercialisation and acquisition. International Journal of Business Innovation and Research, 5(3), 298-317. doi:

POWELL, W., White, D., Koput, K., Owen-Smith, J. (2005). Network dynamics and field evolution: the growth of interorganizational collaboration in the life sciences. American Journal of Sociology, 110(4), 1132-1205. doi:

SANDULLI, F. D., Fernandez-Menendez, J., Rodriguez-Duarte, A., Lopez-Sanchez, J. I. (2012). Testing the Schumpeterian hypotheses on an open innovation framework. Management Decision, 50(7), 1222-1232. doi:

SCHROLL, A., Mild, A. (2011). Open innovation modes and the role of internal R&D: An empirical study on open innovation adoption in Europe. European Journal of Innovation Management, 14(4), 475-495. doi: 10.1108/14601061111174925

TEIRLINCK, P., Poelmans, E. (2012). Open innovation and firm performance in small-sized R&D active companies in the chemical industry: the case of Belgium. Journal of Business Chemistry, 9(3), 117-132. Available at

VAN DE VRANDE, V., de Jong, J. P. J., Vanhaverbeke, W., de Rochemont, M. (2009). Open innovation in SMEs: Trends, motives and management challenges. Technovation, 29(6-7), 423-437. doi: 10.1016/j.technovation.2008.10.001

VAN DER MEER, H. (2007). Open innovation-the Dutch treat: challenges in thinking in business models. Creativity and Innovation Management, 16(2), 192-202. doi:

WEST, J., Gallagher, S. (2006). Challenges of open innovation: the paradox of firm investment in open-source software. R&D Management, 36(3), 319-331. doi:

WIKLUND, J., Shepherd, D. (2003). Knowledge-based resources, entrepreneurial orientation, and the performance of small and medium-sized businesses. Strategic Management Journal, 24(13), 1307-1314. doi:




How to Cite

Michelino, F., Caputo, M., Cammarano, A., & Lamberti, E. (2014). Inbound and Outbound Open Innovation: Organization and Performances. Journal of Technology Management & Innovation, 9(3), 65–82.



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