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Today firm’s competitiveness depends on the development of proprietary technology and its integration to commercial technological products. Experiences and case studies show that the micro, small and medium firms (MIPYMES, in Spanish) develop technological products collaborating with public universities. In this work it is presented the colaborative technological product development process phases focusing in the identification of the diverse obstacles occurring along the process. Diverse technical, organizational and communication aspects that affects the project development are discussed. The resistances or barriers to the development make it difficult and could cause project abandon sometimes. This empirical and exploratory research is conducted under the reference of the technological project management model developed and used at the Centro de Ciencias Aplicadas y Desarrollo Tecnológico (CCADET) of the Universidad Nacional Autónoma de México (UNAM).